Bone Health Facts: Why We Start The Conversation Early
• 1 in 2 women will develop osteoporosis.
• 1 in 3 will become too frail to live independently.
• Of those who fracture a hip, 50% won't fully regain function... and 30% won't survive the year that follows.
These aren't rare outcomes. They're common ones, and largely preventable when the conversation starts early enough.
Bone loss can begin as early as 35.
Estradiol and testosterone (the hormones that decline during perimenopause, menopause, and andropause) are foundational to bone density in both women and men. The standard recommendation is to screen at 65, but by then, significant loss has often already occurred and medication becomes the primary tool.
What actually moves the needle:
• Hormonal balance
• Nutrition
• Mechanical load (Resistance training,
weight-bearing movement)
If you're over 35 and navigating hormonal shifts, or carry additional risk factors, this belongs in your health conversation now — not later.
And if you've already been told you have osteopenia or osteoporosis, that's not the end of the story. With the right support, reversal is possible — or at minimum, meaningful preservation of what you have.
Earlier screening is especially important if any of these risk factors apply to you:
• History of hormonal birth control
• Irregular periods
• Years in perimenopause or menopause without hormone support
• Low muscle mass or no strength training
• Long-term steroid use (prednisone)
• PPI use for reflux
• SSRI use
• Hormone blockers
• Smaller body frame
• Weight loss due to GLP-1s
• Hysterectomy without hormone replacement
• Low protein intake
• History of smoking or alcohol consumption
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Kore Density Is On The Way
We made our own supplement — because what's on the market isn't good enough.
Most bone supplements are under-dosed, missing key cofactors, or require a handful of capsules just to reach therapeutic levels. Kore Density is formulated to support bone remodeling and structural integrity properly.
What's in it:
1. Vitamin C 500mg
Essential for collagen formation — the structural framework that gives bone its strength and allows minerals to bind properly.
2. Boron 3mg
Supports calcium retention and helps regulate vitamin D and estrogen activity — especially important as hormones decline in perimenopause and menopause.
3. Strontium 200mg
Supports bone formation and helps reduce bone breakdown, promoting stronger overall density over time.
4. Manganese 1mg
Required for cartilage and connective tissue formation and supports the enzymes involved in bone remodeling.
5, Calcium 350mg
The primary mineral that gives bone its hardness and structure.
Recommended for:
Dr. Uppal recommends Kore Density for patients who have been referred for a DEXA scan and diagnosed with osteopenia or osteoporosis (including borderline cases).
Expected release: End of May.
If you're over 35 and have never had a bone density scan, it's worth a conversation. Message us through your patient portal or bring it up with Dr. Uppal at your next appointment to see if screening makes sense for you.
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This Month, We're Talking Peptides
These two peptides are usually discussed separately, but together, they might be the most underused tool in medicine.
BPC-157 repairs tissue and reduces inflammation at the injury site. TB-500 promotes regeneration throughout the body. Used together, they work on the injury locally and systemically at the same time.
This one is for:
• The rotator cuff that still isn't right six months later
• The active person who keeps re-injuring the same spot
• Anyone who's been injured longer than they should be
But wait — isn't BPC-157 a gut peptide?
Yes. It also works exceptionally well at the tissue level.
Note: This will help you heal. It won't fix what got you here. Adjust the mechanics, do shockwave, or you'll be back with the same thing.
If you know someone who's been dealing with an injury longer than they should — send them this.
