Creatine + Summer Travels

Summer travel is exciting, but crossing time zones takes a real toll. Jet lag isn't just tiredness. It's your brain and body running on empty while your circadian rhythm tries to catch up!

Most people think of creatine as a gym supplement. Emerging research shows it does something powerful for the brain under stress, and sleep deprivation from travel is exactly that kind of stress. Creatine helps your cells rapidly regenerate energy (ATP) when your normal rhythms are disrupted.

In a 2024 study, participants given a single high dose of creatine during sleep deprivation showed nearly 25% faster mental processing and significant short-term memory improvements.

How to use it for travel:
Take 20g on the day of a long flight or upon arrival to support jet lag and support cognitive function. Benefits peak around 4 hours and can last up to 9.

Already taking 5-10g of creatine a day? Start loading (20g) 5–7 days before you leave so your stores are saturated before you even board the plane.

Nothing replaces good sleep, but creatine gives your brain a real backup when travel makes that impossible.

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June Availability Notice

​Dr. Uppal will be out of town June 5th–17th. The clinic will remain open and prescriptions and messages will still be attended to during this time.

Kore Membership perks, including supplement pickups and in-office services, will remain available during normal business hours with Sarah.

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This Month's Peptide

​​Retatrutide is one of the most exciting next-generation peptides in metabolic medicine right now, and for good reason.

It's a triple agonist, meaning it activates GLP-1, GIP, and glucagon receptors simultaneously; three separate pathways that influence appetite, insulin response, and energy use. Most medications only target one or two of these. Retatrutide works on all three at once, which is what makes it such a powerful tool for metabolic reset.

This peptide is great for:
• Stubborn weight that doesn't respond to diet and lifestyle alone
• Insulin resistance or blood sugar dysregulation
• Metabolic dysfunction associated with fatty liver
• Inflammation tied to excess adiposity

Phase 3 trials are also evaluating its potential for obstructive sleep apnea, knee osteoarthritis, type 2 diabetes, and cardiovascular and kidney outcomes, which tells you just how far-reaching its metabolic effects are.

One important note:
Retatrutide is not a standalone solution. With proper protein intake and resistance training, individuals can preserve or build lean muscle while losing fat, but the foundation matters. Hormonal imbalances, gut health, and nutrient status all need to be assessed first. This is why we always look at the full picture before recommending it.